Barbiturate Detection During Detection Period Is Important
Barbiturates are crystalline, odorless powders with a faintly bitter taste. They have a depressant action on the central nervous system and large doses can directly suppress the medullary respiratory center. There are a number of drugs in this category that have been classified as long acting, short acting, intermediate acting and ultra short acting.
Barbiturates are rapidly absorbed from the intestine including the rectum and also from the sub cutaneous tissues. They are concentrated in the liver for a short time, and then it is evenly distributed in the body fluids. Barbiturate detection is mostly via Barbiturate Urine Screen.
They are metabolized in the liver and excreted in urine. Barbiturates, alcohol and carbon monoxide produce irreversible brain damage and yet the patient survives for a sufficiently long period so that they are completely metabolized or excreted before death occurs. The detection period of drug depends on the type of drug and the amount of drug consumed.
Usually all the drug is excreted in urine depending on its metabolism and urine is the best screening sample that can be used for detecting barbiturate. You have to understand that it would be only a sensitive test and a confirmatory test must be done in the lab to ascertain your findings of the barbiturate drug screening test. In some cases people might have used barbiturate drug wipe and therefore you should be using specimen validity testing to ascertain the integrity of the sample. It is very important that you work with the detection period of the drug, for unless the drug use is chronic, they do not tend to show up post detection period.
Apart from the screening test in urine, the clinical signs must correlate with your findings because sometimes the drug would have been consumed for therapeutic reasons. It is also essential to find out the exact formulation of the drug consumed to confirm your positive findings.
Tags: barbiturate detection, barbiturate drug screening, barbiturate drug wipe, barbiturate urine screen, specimen validity testing
